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Comparative Research Studies
Substituting corn oil in your diet for butter and other fats and
oils high in saturated fat will lower your cholesterol.

 
In human clinical trials that compared diets equal in fat content, with one diet containing corn oil and the other a high saturated fat or oil, the corn oil diet lowered cholesterol about 1% for each gram of corn oil substituted. One tablespoon of corn oil contains 14 grams of corn oil, so a daily substitution of 1 tablespoon of corn oil for butter or other high saturated fat product, could lower your cholesterol about 15%.
 
The suggested substitution of corn oil will decrease saturated fat in your diet and increase polyunsaturated fat. This will have a beneficial effect on your cholesterol, and reduce your risk of coronary heart disease:
 
“polyunsaturated fatty acids reduce LDL cholesterol levels when substituted for saturated fat acids in the diet. Polyunsaturated fatty acids also can cause small reductions in HDL cholesterol when compared with monounsaturated fatty acids, especially when present in high amounts in the diet. Controlled clinical trials indicated that substitution of polyunsaturated fatty acids for saturated fatty acids reduces risk for CHD."1
Fifteen controlled human studies with over 1,000 subjects have compared diets in which corn oil was substituted for butter, beef tallow or other oils. In 14 of those studies, cholesterol levels improved. Three of those studies are summarized below:
Study Participants Corn Oil Diet compared to Diet Containing: Time on Diets Amount of Corn Substituted (Tablespoons)* Cholesterol
(Mean Concentration)
Total LDL HDL
1. Ng et al. 83 subjects (aged 20-34)

22 Females
61 Males

Coconut oil 35 days

2.9

189
Vs
122
119
Vs
69
52
Vs
38
reduced
 36%
reduced
42%
reduced
26%
2. Insull et al. 61 subjects (ages 20-64)

35 Females
26 Males

Normal Diet 35 days 0.8
170
Vs
152
97
Vs
86
56
Vs
50
reduced
11%
reduced
12%
reduced
11%
3.Wardlaw & Snook, 1990

17 males

Butter 35 days 2.1
243
Vs
191
177
Vs
132
43
Vs
42
reduced
21%
reduced
26%
reduced
3%
* Calculated by comparing the amounts of Polyunsaturated Fatty Acids in the two diets
1. Ng TKW, Hassan K, Lim JB, Lye MS, Ishak R. Nonhypercholesterolemic effects of a palm-oil diet in Malaysian volunteers. Am J Clin Nutr. 1991 Apr; 53(4 Suppl):1015S-1020S.
2. Insull W Jr, Silvers A, Hicks L, Probstfield JL. Plasma lipid effects of three common vegetable oils in reduced-fat diets of free-living adults. Am J Clin Nutr. 1994 Aug;60(2):195-202.
3. Wardlaw GM, Snook JT. Effect of diets high in butter, corn oil, or high-oleic acid sunflower oil on serum lipids and apolipoproteins in men. Am J Clin Nutr. 1990 May;51(5):815-21.
1National Cholesterol Education Program, National Heart Lung and Blood Institute, National Institutes of Health. Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). NIH Publication No. 02-5215. http://www.nhlbi.nih.gov/guidelines/cholesterol/index.htm. 2002
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